Open Targets

Drug target discovery and prioritisation platform

This MCP provides a purpose-built interface and instructions to access and interpret the data and analyses in the Open Targets Platform. The Open Targets Platform is a comprehensive tool that supports systematic identification and prioritisation of potential therapeutic drug targets, integrating publicly available datasets to build and score target-disease associations. It also integrates relevant annotation information about targets, diseases/phenotypes, drugs, variants, GWAS and molecular QTL studies, and credible sets, as well as their most relevant relationships.

Install

1Add the server to Claude Code

claude mcp add --transport http open-targets https://mcp.platform.opentargets.org/mcp

These instructions target Claude Code. Check the publisher's documentation for support in other Claude surfaces; a valid server URL alone does not establish compatibility.

JSON.mcp.json for a shared project

Commit this file so everyone on the project gets the same server.

{
  "mcpServers": {
    "open-targets": {
      "type": "http",
      "url": "https://mcp.platform.opentargets.org/mcp"
    }
  }
}

Tools

  • get_open_targets_graphql_schema
  • search_entities
  • query_open_targets_graphql
  • batch_query_open_targets_graphql

Discussion

Discussion

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